Studies on selective fibrinolytic therapy by using autogenous plasmin.
نویسندگان
چکیده
منابع مشابه
Evaluation of fibrinolytic therapy by measuring cross-linked fibrin derivatives and plasmin-alpha 2-plasmin inhibitor complex in plasma.
Plasma levels of alpha 2-plasmin inhibitor (alpha 2PI), plasmin-alpha 2PI complex and cross-linked fibrin derivatives (XDP) were measured in 8 patients (12 episodes) with thromboembolic disorders on the initial administration of urokinase. In conjunction with a decrease in plasma alpha 2PI activity and antigen, plasmin-alpha 2PI complex increased following urokinase infusion in all cases except...
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The mastoid cavity after ''debridement" becomes one of the main causes of failure in the follow-up of tympanoplasty when left unobliterated. Various trials have been made to seek an effective method of filling up the cavity. We conducted a study on mastoidplasty using autogenous bonemarrow and free skingraft and found the results were satisfactory. 15 patients were observed clinically, histolog...
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To explore the possibilities of fibrinclytic therapy of coronary thrombosis, experimental studies were carried out to document lysis of coronary thrombi and to investigate the effect of fibrinolytic blood upon inyocardial infarction. Serum-induced coronary thrombi were produced by a new technic and were followed by serial coronary arteriography. Control animals were compared to animals in which...
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Binding of plasmin(ogen) to rat C6 glioma cells is saturable and kringle-domain dependent. This interaction was studied as a model of plasmin(ogen) receptor interactions in nucleated mammalian cells. Apparent 125I-plasmin dissociation from C6 cell binding sites was slow; however, the dissociation rate was increased when the solution contained diisopropyl phosphoryl-plasmin (0.3 microM), fibrino...
متن کاملFibrinolytic cross-talk: a new mechanism for plasmin formation Short title: Fibrinolytic cross-talk
*These authors contributed equally to this work (alphabetical order). Abstract Fibrinolysis and pericellular proteolysis depend on molecular co-assembly of plasminogen and its activator on cell, fibrin or matrix surfaces. We report here the existence of a fibrinolytic cross-talk mechanism bypassing the requirement for their molecular co-assembly on the same surface. First, we demonstrate that d...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1989
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.20.167